Periodontal Disease and the Risk for Cardiovascular Disease
牙周病和心血管疾病有關
牙痛索命！男子敗血症亡 【4/14 2009】
〔本報訊〕蛀牙竟成索命殺手！媒體報導，一名40歲的男子忍牙痛一週都未治療，頸部明顯腫脹，急診就醫時意識清醒，經檢查發現是臼齒等多顆蛀牙牙神經壞死引起感染。最後因為深頸部感染，就連胸腔都有膿，雖經緊急動手術引流，並施以抗生素治療，仍在一週後因敗血症而不治喪命。牙醫師提醒民眾，牙齒冷熱敏感或牙痛應該立即就醫治療，以免牙神經爛掉，增加感染風險。
這是前幾天(2009-04-14) 的大新聞，但偉大的臺灣同胞一如往昔，覺得牙痛不是病，況且自己身體健康沒那麼倒楣，所以過兩天就給它忘記啦~~ (門診也沒比較熱鬧，Haha~~)
但是各位，沒有牙痛也要注意口腔保健，預防牙周病，才能健康長壽！因為口腔內感染(牙周病是慢性發炎)和心血管疾病有關！
**Periodontal Disease and the Risk for Cardiovascular Disease
Selected from Medscape Best Evidence Reference (2009-04-13)
Humphrey LL, Fu R, Buckley DI, Freeman M, Helfand M. Periodontal disease and coronary heart disease incidence: a systematic review and meta-analysis. J Gen Intern Med. 2008;23:2079-2086.
牙周病極常見，但醫師们很少去注意這問題。高蛀牙率、缺(多顆)牙、牙周病和心血管健康有關(負相關)，醫師们應關切患者上述的口腔狀況。
由於嚴重牙周病可引起血管內發炎，增加2.31倍代謝症候群罹患率；所增加的發炎物質包括血清中C-reactive protein (CRP) ＞40%，
以及plasma fibrinogen血漿纖維蛋白原.
Background
Dental and periodontal disease is very common, but this significant public health problem receives little attention from physicians. Physicians should be concerned about the high rates of caries, tooth loss, and periodontal disease because these oral conditions are associated with significant negative health outcomes.
In one analysis that adjusted for traditional risk factors, the prevalence of the metabolic syndrome was 2.31 times higher among patients with severe periodontal disease compared with adults without periodontal disease, due to an increase in the degree of intravascular inflammation. Periodontal disease has been associated with increases in the levels of inflammatory markers, including an increase in serum C-reactive protein (CRP) levels of over 40% and an increase in plasma fibrinogen levels.[5] However, this same study failed to demonstrate a significant relationship between periodontal disease and serum lipid values.
Clinical Pearls 臨床指引
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